Gene Therapy Training Network (GTTN) and Instructional Transfer Platform (ITP)

The Gene Therapy Training Network (GTTN) will enable development of courses related to gene therapy, transfer of these courses to other NIIMBL members, and standardization of course content and curriculum for professionals.
Categories
Cell and Gene therapies
Drug substance
Incumbent worker training
Project status
100% Completed

Industry Need

Gene therapy is a rapidly developing treatment option. Despite this growth, there are limited opportunities for training in the area of gene therapy vector manufacturing.

Solution

The solution is the Gene Therapy Training Network (GTTN). The network will enable development of courses related to gene therapy, transfer of these courses to other institutions within the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), and standardization of course content and

curriculum for professionals.

Outputs/Deliverables


  • Course Lab Protocols – Available upon request
  • Instructor's Manual – Available upon request
  • Course Transfer SOP – Available upon request
  • AAV Production Protocols – Available upon request


Impacts

Transfer of the "Hands-On cGMP Biomanufacturing of Vectors for Gene Therapy" course to other institutions and regions, enabling opportunities for employees to develop skills in the complex processes required for cGMP production of gene therapy vectors

Development of comprehensive set of courses related to gene therapy, and standardization of gene therapy course content and curriculum for professionals

Publications

Overton, L., Boi, C., Shastry, S., Smith-Moore, C., Balchunas, J., Sambandan, D., & Gilleskie, G. (2023). Development and Delivery of a Hands-On Short Course in Adeno-Associated Virus Manufacturing to Support Growing Workforce Needs in Gene Therapy. Human Gene Therapy, 34(7-8), 259-272. https://doi.org/10.1089/hum.2022.235

Additional Project Information (Members Only)

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Project Lead

North Carolina State University

North Carolina State University

Participating Organizations

Texas A&M University System

Texas A&M University System