A Novel Beads-free CAR T-Cell Manufacturing Platform
Chimeric antigen receptors (CARs) T-cell therapy has become an important approach for cancer treatment. This project aims develop a novel perfusion-based, beads-free, bioreactor system as a new platform for CAR T cell manufacturing.
Categories
Cell and Gene therapies
Project status
100% Completed
Industry Need
Chimeric antigen receptors (CARs) T-cell therapy has become an important approach for cancer treatment.
Solution
Develop a novel perfusion-based, beads-free, bioreactor system as a new platform for CAR t-cell manufacturing.
Outputs/Deliverables
Developed an automatable, scalable, and closed bioreactor system and process for T-cell activation and expansion.
Impacts
The development of this novel perfusion-based system would facilitate scaling the manufacturing of CAR T cells for different users.
Publications
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