Driving U.S. leadership in biopharmaceutical manufacturing

Big Data Program Survey

Share your input on improving interoperability and developing industry-wide data standards that enhance biomanufacturing productivity.

 Deadline: January 30, 2026

NIIMBL eXperience Student Applications

Help first- and second-year college students explore careers in biopharma manufacturing.

Deadline: February 5, 2026

What we do

Advance biopharmaceutical manufacturing innovation

Collaborate on innovative manufacturing platforms and technologies that accelerate the development and manufacture of life-saving medicines and medical countermeasures, enhance national economic security, and support response to biothreats

Solve industry challenges

Help companies de-risk the adoption and implementation of new technologies and approaches for development and manufacturing

Develop the skilled workforce of the future

Strengthen the U.S. economy by cultivating a world-leading biopharmaceutical workforce that meets the industry’s needs through novel training and education programs

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Together with our partners...we will ultimately enable life-saving and life-enhancing therapies to be brought to patients more quickly.

Udit Batra, President & CEO, Waters

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Current solicitations

We achieve our mission through an RFx process that aims to advance technical and workforce development projects:

  • Request for Proposal (RFP): A solicitation sent to the entire NIIMBL community that is to result in funding of activities
  • Request for Information (RFI): An open invitation for organizations to share information; not directly associated with funding
  • Request for Applications (RFA): A focused solicitation to particular organizations to submit an application intended to result in funding of activities

See all opportunities
RFA: Viral Vectors Capsid Titer
RFA: Faculty Fellows
RFP: Project Call 9.1

RFA: Viral Vectors Capsid Titer

RFA: Viral Vector Capsid Titer Interlab Study (RFA2025.03)

This opportunity is now closed.

NIIMBL is pleased to announce this Request for Application (RFA) to participate in the Viral Vector Program interlab study to evaluate whether utilizing the new United States Pharmacopeia (USP) AAV9 Reference material as a calibrant can improve the accuracy and precision of AAV9 capsid titer measurements from commercial Enzyme-Linked Immunosorbent Assay (ELISA) kits.

Study Goals

  • Compare the accuracy and precision of AAV9 capsid titer measurements across multiple commercial ELISA kits when the standard curve is comprised of (1) the USP calibrant vs. (2) the kit-included standard.
  • Compare intra- and inter-laboratory variability using the USP calibrant vs. existing ELISA kit standards.
  • Support regulatory alignment and qualification of the USP calibrant for broader industry use.

Learn more

RFA: Faculty Fellows

NIIMBL is pleased to announce the pilot of a faculty sabbatical in industry program. The NIIMBL Faculty Fellows program provides financial support for faculty or instructional staff at universities and community colleges to pursue a sabbatical either at an industry member (Tier 1 or Tier 2) or at NIIMBL’s Headquarters (NIIMBL HQ) in Delaware to support NIIMBL-led projects.

The NIIMBL Faculty Fellows program closes December 31, 2024.

Learn more

RFP: Project Call 9.1

Concept submissions for Project Call 9.1 are now closed.

NIIMBL is pleased to announce Project Call 9.1, with member- driven and industry-led priority topic areas for technical development proposals.

Technology Topics:

  • Real-Time Monitoring and Advanced Process Analytics for In-Process Control
  • Integrated Modeling and Control Strategies Linking Upstream, Downstream, and Cell Line Development
  • Novel Protein Expression Platforms for Complex and Next-Generation Biotherapeutics
  • Digital and Automation Platforms to Enhance Downstream Development and Filtration Scalability
  • Advanced AI/ML-Driven Strategies for Biopharmaceutical Process Modeling and Optimization

Workforce Development Topics

  • Stimulate Knowledge and Interest in Biopharma Manufacturing Careers
  • Accelerate Career and Leadership Advancement in Biopharma Manufacturing
  • Build an AI-Ready Biopharmaceutical Manufacturing Workforce
  • Pilot Lower-Cost Options for Biopharmaceutical Manufacturing Education
  • Catalyze Cross-Regional Workforce Development Partnerships
  • Build a Future Biopharma Workforce Through Cross-Sector Pathways

Learn More

Current solicitations

We achieve our mission through an RFx process that aims to advance technical and workforce development projects:

  • Request for Proposal (RFP): A solicitation sent to the entire NIIMBL community that is to result in funding of activities
  • Request for Information (RFI): An open invitation for organizations to share information; not directly associated with funding
  • Request for Applications (RFA): A focused solicitation to particular organizations to submit an application intended to result in funding of activities

RFA: Viral Vectors Capsid Titerarrow down

RFA: Viral Vectors Capsid Titer

RFA: Viral Vector Capsid Titer Interlab Study (RFA2025.03)

This opportunity is now closed.

NIIMBL is pleased to announce this Request for Application (RFA) to participate in the Viral Vector Program interlab study to evaluate whether utilizing the new United States Pharmacopeia (USP) AAV9 Reference material as a calibrant can improve the accuracy and precision of AAV9 capsid titer measurements from commercial Enzyme-Linked Immunosorbent Assay (ELISA) kits.

Study Goals

  • Compare the accuracy and precision of AAV9 capsid titer measurements across multiple commercial ELISA kits when the standard curve is comprised of (1) the USP calibrant vs. (2) the kit-included standard.
  • Compare intra- and inter-laboratory variability using the USP calibrant vs. existing ELISA kit standards.
  • Support regulatory alignment and qualification of the USP calibrant for broader industry use.

Learn more

RFA: Faculty Fellowsarrow down

RFA: Faculty Fellows

NIIMBL is pleased to announce the pilot of a faculty sabbatical in industry program. The NIIMBL Faculty Fellows program provides financial support for faculty or instructional staff at universities and community colleges to pursue a sabbatical either at an industry member (Tier 1 or Tier 2) or at NIIMBL’s Headquarters (NIIMBL HQ) in Delaware to support NIIMBL-led projects.

The NIIMBL Faculty Fellows program closes December 31, 2024.

Learn more

RFP: Project Call 9.1arrow down

RFP: Project Call 9.1

Concept submissions for Project Call 9.1 are now closed.

NIIMBL is pleased to announce Project Call 9.1, with member- driven and industry-led priority topic areas for technical development proposals.

Technology Topics:

  • Real-Time Monitoring and Advanced Process Analytics for In-Process Control
  • Integrated Modeling and Control Strategies Linking Upstream, Downstream, and Cell Line Development
  • Novel Protein Expression Platforms for Complex and Next-Generation Biotherapeutics
  • Digital and Automation Platforms to Enhance Downstream Development and Filtration Scalability
  • Advanced AI/ML-Driven Strategies for Biopharmaceutical Process Modeling and Optimization

Workforce Development Topics

  • Stimulate Knowledge and Interest in Biopharma Manufacturing Careers
  • Accelerate Career and Leadership Advancement in Biopharma Manufacturing
  • Build an AI-Ready Biopharmaceutical Manufacturing Workforce
  • Pilot Lower-Cost Options for Biopharmaceutical Manufacturing Education
  • Catalyze Cross-Regional Workforce Development Partnerships
  • Build a Future Biopharma Workforce Through Cross-Sector Pathways

Learn More

See all opportunities

Who we are

Our members are stakeholders from across the biopharmaceutical manufacturing ecosystem, including large and small companies, academic institutions, and nonprofits.

Members have the opportunity to collectively revolutionize current biomanufacturing platforms, processes, and educational programs and share in the benefits of these transformative solutions.

Members talking at a NIIMBL event

Why NIIMBL

The NIIMBL ecosystem’s collaborative efforts to accelerate innovative manufacturing technologies help to:

  • Ensure a secure, integrated domestic supply chain
  • Enable lifesaving and life-enhancing therapies to reach patients more quickly
  • Strengthen biodefense
  • Cement the United States’ leadership in the global manufacturing industry
  • Increase the biopharmaceutical industry’s global competitiveness

About biopharmaceuticals and biomanufacturing

About biopharmaceuticals and biomanufacturing

Biopharmaceuticals are medicines and medical countermeasures that save, sustain, and improve lives. They:

  • are manufactured in, extracted from, or derived from biological sources and require complex manufacturing process.
  • treat and prevent some of the most prevalent and debilitating diseases affecting human health, including cancer, diabetes, autoimmune disorders, and bacterial and viral infections, making biopharma one of the most valuable and important business sectors in the United States.
  • play a crucial role in protecting the United States from health threats.
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(NIIMBL) provides a structured space to experiment with approaches that will lead to our ability to rise to today's challenges and build a better future.

Mike Kress, Sr. Vice President Development Sciences and Clinical Supply,
Merck & Co., Inc.

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Become a Member

We offer a variety of membership options that give you the flexibility to choose your organization’s level of engagement based on technology interests and priorities.